020.305 (N) Biochemistry
Prerequisite: Chemistry 030.104
Corequisite: Chemistry 030.201
Instructors: Hill, Bessman, Schildbach
4 credits, Fall

020.306 Cell Biology
How the molecules of living systems are organized into organelles, cells, tissues, and organisms will be explored, as well as how the activities of all of these are orchestrated and regulated to produce "life"--a phenomenon greater than the sum of its parts. Considerable emphasis is placed on experimental approaches to answering these questions. Topics covered include biological membranes, cytoskeletal elements, cell locomotion, membrane and protein traffic, the nucleus, second messengers, signal transduction, cell growth, the cell cycle, the extracellular matrix, cell contacts and adhesion, intercellular communication, epithelial structure and function, and the cell biology of early development and organ function.
Prerequisite: 020.305
Instructors: Schroer, Wendland
4 credits, Spring

020.310 Developmental Neurobiology
This is an upper-level course focused upon the cellular and molecular mechanisms underlying nervous system development. Topics include the specification of neural tissues, genesis and differentiation of individual neurons, extension of axons and axon guidance, formation of synaptic connections, maturation of neuronal circuits, and plasticity of neuronal circuits in the adult nervous system. The format of the course will be a mix of lectures and discussions of papers. Reading will include selected articles from the recent literature.
Prerequisites: 080.304 or permission of instructors.
Instructors: Norris / Kirkwood
3 credits, Spring

020.311 Enzymes & Proteins
Prereq: 020.305 (Limit 50)
This course will emphasize the structure and function of enzymes and other proteins.  It will build on the fundamentals covered in 020.305 Biochemistry.  Some enzymes will be discussed in detail and some of the experimental methods used to understand mechanisms of action will be explored.
Instructor: Brand
Spring, odd years

020.315 Biochemistry Laboratory
Corequisites: 020.305
Instructor: Horner
2 credits, Fall
(First lab section meeting 9/10/2007)

020.316 Cell Biology Laboratory
This course will reinforce the topics presented in 020.306 Cell Biology through laboratory exercises which use visible and fluorescence microscopy to study chromosomes, cell organelles, cell surface receptors, contractile proteins, and microfilaments.
Prerequisites: 020.305, 020.315
Corequisite: 020.306
Instructor: Horner
2 credits, Spring

020.317 Signaling in Development and Disease
An advanced undergraduate level seminar on current topics on signal transduction mechanisms underlying neuronal morphology, development and function. The proper functioning of the nervous system relies on the establishment of precise neuronal circuits through a developmental program including proliferation, neuronal migration, axonal growth and neuronal survival. This course pertains to the extracellular cues and downstream neuronal signaling pathways that coordinate these key events during neuronal development. The course will also cover the role of aberrant signaling mechanisms in neuronal degeneration and disease.
Instructor: Kuruvilla
3 credits, Fall

020.324 (N) Bioinformatics / DNA Microarray Technology
Limit: 18
Recommended: 020.330 , preferred 020.340
Instructor: Cunningham
2 credits, Spring / even years

020.330 (N) Genetics
Prerequisite: 020.305
Instructors: Hoyt, Cunningham
3 credits, Fall

020.332 Plant Biochemistry
This course will emphasize plant biochemistry, including fundamental physiological processes of plants, cell structure and function, light capture and photosynthesis, plant growth and development, and the metabolism of minerals and nitrogen.
Prerequisites: 020.305-306
Instructors: Moudrianakis, Horner
2 credits, Spring

020.333 (N) Adaptations of Plants to their Environment
Limit: 24
Prerequisites: 020.252-253 or AP Biology credit
Instructors: McCarty
2 credits, Spring

020.340 Genetics Laboratory
This laboratory explores the genetics of living organisms, and students will therefore be required to return to lab on succeeding days to observe and record the results of their experiments.
Limit: 40 per section.
Corequisite: 020.330.
Instructor: Kondo
2 credits, Fall

020.345 (N) Microbial Patheogenesis
Limit: 50
Prerequisites: 020.305-306, 020.330
Instructors: Beemon, Schildbach
3 credits, Spring

020.346 Immunobiology
A course for upper-level undergraduates that will introduce them to immunochemistry, immunobiology, and clinical immunology. Emphasis is placed on the language, concepts, and experimental methodology of modern immunology and the application of this information to specific human diseases.
Prerequisite: 020.305, 020.306
Corequisite: 020.330
Instructor: Edidin
3 credits, Spring

020.347 (N) AIDS
This course will cover the biology of the infectious agent that causes AIDS, the effects of HIV on the immune system, the search
for an HIV vaccine, and the pharmacology of the anti-viral agents that are used to supress HIV infection.
Prerequisite: 020.306
Instructor: Schroer
2 credits, Fall (odd years)

020.349 (N) Epidemics and Pandemics
The course will examine a dozen infectious diseases that have demonstrated a capacity for causing widespread illness and death.
Prerequsite: 020.330 or permission required.
Instructor: Shildbach
2 credits, Spring

020.350-359 Advanced Seminars
The department will offer advanced seminars in the areas of molecular, cell, organismal, and population biology. Seniors should consult the course offerings each semester concerning the specific seminars being offered.
Permission required
2 credits

020.350 (N) Advanced Seminar: Topics in Modern Medicine
Limit: 25 per section
Prerequisite: Post-Bac Students only
Instructor: Salmon
Permission required
1 credit, Fall

020.363 (N) Developmental Biology
Development of invertebrates, vertebrates and plants. The course will emphasize the experimental bases for the fundamental concepts of development.
Prerequisites: 020.305-306; 020.330
Instructors: Van Doren
3 credits, Spring

020.365 (N) Introduction to the Human Skeleton
This course will provide a basic understanding of human skeletal biology.
Instructor: Ruff
3 credits, Spring

020.366 (N) Human Evolution
A close look at the fossil evidence for human evolution.
Limit: 25
Prereq: 020.207 or 020.379 or Permission required.
Instructor: Teaford
3 credits, Spring

020.367 (N) Primate Behavior & Ecology
A close look at our closest living relatives. Topics include: past and present distributions of primates; primate taxonomy, feeding and diet, reproduction, social organization, community relationships and conservation.
Limit: 30
Prerequisites: 020.151-152 or 200.146 or 020.270 or Permission Required
Instructor: Teaford
3 credits, Spring / Even years

020.373 Developmental Biology Laboratory
The course will include laboratory study of developing vertebrate and invertebrate embryos, analysis of embryogenesis at the molecular, cellular, tissue, and organ levels.
Corequisite: 020.363
Instructor: Kondo
2 credits, Spring

020.375 (N) Human Anatomy
Limit: 24
Instructor: Teaford
3 credits

020.379 (N) Evolution
An exploration of the principles of natural selection and an examination of the origin of species from both the geologic record (paleontology) and the genetic record. Also the role of DNA as the driving force for evolution.
Prerequisites: Cell Biology (020.306) and Genetics (020.330).   Students who have not had genetics may get permission for the course after talking to the instructor.
Instructor:  Norris
3 credits, Fall

020.380 Eukaryotic Molecular Biology
The class will read and discuss original research papers highlighting important developments in molecular biology
Limit:40
Prerequisite: 020.330
Instructors: Beemon, Moudrianakis
3 credits, Fall

020.395 Fundamentals of Biological Light Microscopy
Introduction to the principles, practice, and application of light microscopy (LM) to biomedical research. The course will cover light optical theory; instrumentation design, use, and applications; and will afford students 'hands-on' experience in both specimen preparation and microscope operation (including epifluorescence, confocal, and deconvolution light microscopes).
Prerequisite: Permission of instructor
Instructor: McCaffery
Intersession / even years

020.397 Fundamentals of Biological Electron Microscopy
Introduction to the principles, practice, and application of electron microscopy (EM) to biological/cell biological research. The course will cover electron optical theory; instrumentation design, use, and applications; and will afford students 'hands-on' experience in both specimen preparation and electron microscope operation (including both transmission and scanning electron microscopes).
Prerequisite: Permission of instructor.
Instructor: McCaffery
Intersession / odd years.

020.401-402 Advanced Seminar in Molecular and Cellular Biology
This is a weekly seminar designed for graduate students enrolled in the B.A./M.S. and Ph.D. programs. The seminar involves students presentations of research and discussion of topics of current interest in the field .
Instructor: Staff
3 credits, 020.401 is offered in the fall, and 020.402 is offered in the spring

020.402 Seminar: Current Progress in Cellular and Molecular Biology & Biophysics
Prerequisite: BA/MS candidates only
Instructor: Staff
3 credits, Spring

020.420 (N) Build-A-Genome
Prerequisite: Permission of instructor.
Must understand fundamentals of DNA structure, DNA electrophoresis and
analysis, Polymerase Chain Reaction (PCR) and must be either a)
Experienced with molecular biology lab work or b) Adept at programming
with a biological twist. In this combination lecture/ laboratory
"Synthetic Biology" course students will learn how to make DNA building
blocks used in an international project to build the world's first
synthetic eukaryotic genome, Saccharomyces cerevisiae v. 2.0. Please
study the wiki www.syntheticyeast.org for more details about the
project. Following a biotechnology boot-camp, students will have 24/7
access to computational and wet-lab resources and will be expected to
spend 15-20 hours per week on this course. Advanced students will be expected to contribute to the computational and biotech infrastructure. Successful completion of this course provides 3 credit hours toward the supervised research requirement for Molecular and Cellular Biology majors, or 2 credit hours toward the upper level elective requirement for Biology or Molecular and Cellular Biology majors.
Instructor: Boeke, Bader, Ostermeier
4 credits, Fall and Spring

020.441 Mentoring in Biology
Prerequisite: Consent of adviser required
Instructor: Pearlman, Shingles
3 credits, Fall - plus 1 add'l hour TBA

020.451 Build-A-Genome Mentor In addition to providing and sequencing DNA segments like regular B-a-G students, mentors will help prepare and distribute reagents, and maintain a Moddle site to track student reagent use and productivity. Mentors will also be expected to mentor specific students who are learning new techniques for the first time, contribute to the computational and biotech infrastructure associated with Build-a-Genome, and pursue at least one independent research project. Successful completion of this course provides 3 credit hours toward the supervised research requirement for Molecular and Cellular Biology majors.
Instructor: Boeke, Bader
4 credits, Fall and Spring

020.501-502 Introduction to Independent Study in Biology
An independent course of study may be pursued under the direction of an adviser on those topics not specifically listed in the form of regular courses.
Freshmen and sophomores only
Prerequisite: Consent of adviser required

020.503-504 Introduction to Research in Biology
Usually students are not prepared for research or independent study until their junior year. These courses are offered to accommodate the exceptional freshman or sophomore who has already had extensive laboratory and/or course experience enabling him/her to undertake advanced work.
Prerequisite: Freshmen and sophomores only

020.511-512 Independent Study
An independent course of study may be pursued under the direction of an adviser on those topics not specifically listed in the form of regular courses.
Prerequisite: Consent of adviser required.
Instructor: Staff

020.513-514 Research Problems
Original laboratory investigations on biological problems. Letter grades in research are given only for work done directly with a member of the department faculty.
Prerequisite: Permission of faculty member in charge

020.650 Eukaryotic Molecular Biology
The class will read and discuss original research papers highlighting important developments in molecular biology
Limit:40
Prerequisite: 020.330
Instructors: Beemon, Moudrianakis
3 credits, Fall

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